Potassium Chloride Extended Release Tablets, USP . Thus, a 99 mg dose of potassium citrate, expressed as potassium, is about 2.5 meq of potassium and 2.5 meq of citrate. Each potassium chloride extended-release tablet provides either 1500 mg of potassium chloride equivalent to 20 mEq of potassium or 750 mg of potassium chloride equivalent to 10 mEq of potassium. Urocit K, a common commercial version, is a crystalline monohydrate sal t so it has a MW of 3×39 (for 3 potassium ions) + 189.1 (for citrate) + 18 for the one water molecule, or 324.1 in all. Increased urinary PH also causes uric acid's more soluble urate ion to form, thus decreasing the risk of uric acid stones. » Potassium Gluconate, Potassium Citrate, and Potassium Guaiacolsulfonate Ammonium Chloride Oral Solution is a solution of Potassium Gluconate, Potassium Citrate, and Ammonium Chloride in a suitable aqueous me-dium. Also, the bicarbonate may reduce bone resorption (release of calcium from bone to blood via action of osteoclasts) and increased renal calcium reabsorption. Total intake would equal 10.12 mEq (253 mEq per 99 mg pill). {42} Usual pediatric dose Potassium chloride, which is shown as KCl, is an ionic solid. POTASSIUM CHLORIDE EXTENDED-RELEASE TABLETS USP Usual adult and adolescent dose Hypokalemia (prophylaxis or treatment) Oral, 6.7 to 20 mEq of potassium (approximately 500 to 1.5 grams of potassium chloride, respectively) three times a day. 2015. Additionally, the question arose as to whether or not potassium citrate and potassium chloride could be used interchangeably; if not, what is the difference in these two salts? The effectiveness of potassium citrate as a potassium supplement was compared to that of potassium chloride in 13 patients with calcium nephrolithiasis treated with thiazide. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 3 Dec 2020) and others. Goal serum potassium level: ∼ 4.0 mEq/L; Expected increase in serum potassium levels: ∼ 0.1 mEq/L after an … Potassium citrate potency is usually expressed as the amount of potassium contained in each tablet or capsule. Prevention of calcium renal stones in patients with hypocitraturia, Urinary alkalinizer when Na-Citrate contraindicated, Acidify urine—lower urine calcium concentration, Reduce odor and rash from ammonia in urine, Synergistic effect with antibacterial activity of methenamine, Treatment/prevention of hypokalemia (if avoiding chloride or acid/base status requiring bicarb), Expectorant; chronic pulmonary diseases complicated by mucus. Ronbo36316 21 Aug 2017. Potassium citrate potency is usually expressed as the amount of potassium contained in each tablet or capsule. Compare Potassium Chloride vs Potassium Citrate head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Potassium citrate and potassium chloride are forms of the mineral potassium prepared in two different ways. It is in the form of a white color, odorless crystal. DESCRIPTION. Citric acid and citrate salts (which contain potassium and sodium) belong to a class of drugs known as urinary alkalinizers. In the monohydrate form it … The answer is no, these are not equivalent products. Citrate, and Ammonium Chloride Oral Solution. The most common obstacle to patient compliance with this medication has historically been dosing frequency, pill size, dyspepsia, and its familiar unpleasant taste. potassium chloride; potassium phosphates, IV; spironolactone; triamterene; Potassium citrate has moderate interactions with at least 97 different drugs. Each mg of chloride is equivalent to Potassium Gluconate, Potassium 0.0282 mEq of Cl. Follow your doctor's orders or the directions on the label. Potassium citrate provides a sustained alkali load compared to the short-term actions of potassium bicarbonate. This document does not contain all possible interactions. The unit is used to describe how different salts can provide equivalent amounts of a particular ion, such as potassium. I saw where one answered 3.5 tablets to make 10meq, Thus 7 x 99 = 6937.5 x 99 = 742.58 x 99 = 792, So if you prefer to take multiple tablets you will have to take 8 to get your 750 mg or 10 meq of potassium. Potassium is a group 1 metal; thus forms a +1 charged cation. Potassium citrate has mild interactions with at least 29 different drugs. Potassium and magnesium citrate are available in supplement form. , 2. Potassium Chloride rated 6.1/10 vs Potassium Gluconate rated 0.0/10 in overall patient satisfaction. Side effects of potassium citrate include nausea, vomiting, diarrhea, stomach pain, headache and dizziness. Therefore, 99 mg divided by 39.0983 (atomic wt of elemental potassium) = 2.53 mEq of potassium. Should antihypertensives be dosed at night? The solid dissolves readily in water, and its solutions have a salt-like taste.Potassium chloride can be obtained from ancient dried lake deposits. If your dose is different, do not change it unless your doctor tells you to do so. A simultaneous decrease in calcium ion activity occurs as a result of increasing calcium complex formation with dissociated anions. Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid with the molecular formula K 3 C 6 H 5 O 7.It is a white, hygroscopic crystalline powder. A direct answer is simple... if you have pills that are each 99 mg and you need 10 mEq, you should take four tabs per day. Potassium citrate's three indications are as follows: What is the difference between it? The following information includes only the average doses of this medicine. Formula: mEq= mg/atomic weight * valence Minerals: Atomic Weight: Valence: Calcium : 40: 2: C hlorine: 35.4: 1: Magnesium: 24.3: 2: Phosphorus: 31 Today I encountered an interesting drug information question regarding the various potassium products that were available. To determine mEq from mg, take the atomic weight of the element & divide it into the mg. Potassium chloride (also known as Sylvite, KCl, or potassium salt) is a metal halide salt composed of potassium and chlorine.It is odorless and has a white or colorless vitreous crystal appearance. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It is available in generic and brand versions. Potassium citrate's three indications are as follows: Oral administration of potassium citrate produces an alkaline load, as the citrate is converted hepatically to bicarbonate. 99 mg is 2.53 meq. I saw where one answered 3.5 tablets to make 10meq. I am getting bored, please fchat with me ;) ;) ;) …████████████████████████████████████████████████████████████████████████████████████████████████. Thiazide treatment alone reduced serum potassium, urinary calcium and citrate without affecting urinary pH. Potassium citrate extended-release tablets USP are supplied as wax matrix tablets, containing 5 mEq (540 mg) potassium citrate or 10 mEq (1080 mg) potassium citrate, for oral administration. Follow your doctor's orders or the directions on the label. Potassium chloride extended-release capsules, USP, 10 mEq is an oral dosage form of microencapsulated potassium chloride containing 750 mg of potassium chloride USP equivalent to 10 mEq of potassium. Unlike potassium chloride, potassium citrate does not have an FDA-approved labeled indication for the treatment of  hypokalemia. Unlike potassium chloride, potassium citrate does not have an FDA-approved labeled indication for the treatment of hypokalemia. Each tablet of KMgCit contained 7 mEq K, 3.5 mEq Mg, and 10.5 mEq citrate; a tablet of potassium chloride contained 7 mEq each of potassium and chloride. Treatment should be discontinued if there is hyperkalemia or a significant rise in serum creatinine. Try searching for what you seek or ask your own question. Potassium Gluconate has a molar weight of 234.246 g/mol, so unfortunately that means 4684.9 milligrams or 8 of those pills. 1. If you have a condition that requires you to limit your intake of potassium and sodium, your doctor may direct you to take a product that is lower in potassium and sodium. Potassium Chloride rated 6.1/10 vs Potassium Citrate rated 8.0/10 in overall patient satisfaction. The dose of this medicine will be different for different patients. It is odorless with a saline taste. The amount of medicine that you take depends on the strength of the medicine. Why can't you lay down after taking a potassium? It can release one electron, which is in 4s sub orbital and produce a +1 cation. Compare Potassium Chloride vs Potassium Gluconate head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Urinary saturatio … Your body uses potassium to help your heart, muscles, kidneys, nerves and digestive system work properly. Still looking for answers? The whole tablet of potassium citrate is coming out on my poops? 3. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. We comply with the HONcode standard for trustworthy health information -, Potassium Citrate Information for Consumers, Potassium Citrate Information for Healthcare Professionals. Thus, a 99 mg dose of potassium citrate, expressed as potassium, is about 2.5 meq of potassium and 2.5 meq of citrate. In dietary supplements, potassium is often present as potassium chloride, but many other forms—including potassium citrate, phosphate, aspartate, bicarbonate, and gluconate—are also used . Typically the potassium citrate salts have a potassium on each of the three anion sites on the citrate molecule. It’s important for various functions in the body like electrolyte and acid-base balance. The MW of citrate anion is 189.1. These combined effects may lead to a transient decrease in urinary calcium, and makes the environment of the urine less conducive to the crystallization of stone-forming salts. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem f… Potassium salts like potassium chloride, potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate are prescribed for such patients. Drugs.com. 1 Eq is 1mol if you are talking about a monovalent ion (like potassium). so 3.95 tablets would be 10 meq, Try the math again10meq is equal to 750 mg. Kaismama's answer is correct. Potassium is useful in regulating heart rate. Krieger NS, Asplin JR, Frick KK, et al. Potassium Citrate (kcit) has long been utilized by physicians to combat stone formation in patients with hypocitraturia or aciduria. Serum potassium concentrations, serum electrolytes (sodium, potassium, chloride and carbon dioxide), and serum creatinine should be monitored every four months during therapy with potassium citrate extended-release tablets (Urocit-K). Potassium citrate is a salt that helps regulate urinary pH levels. Generic potassium citrate is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Accessed 7/31/2015. J Am Soc Nephrol. Electronegativity of potassium is very low, allowing it to form cations by donating an electron to a higher electronegative atom (lik… Following absorption, potassium citrate causes increased plasma bicarbonate concentration, thereby raising blood and urinary pH. Potassium is an essential mineral found in various foods. Potassium and magnesium citrate are of vital importance to your cardiovascular and central nervous systems. Slow-K, potassium chloride extended-release tablets USP, is a sugar-coated (not enteric-coated) tablet for oral administration, containing 600 mg of potassium chloride (equivalent to 8 mEq) in a wax matrix. SLOW-K (potassium chloride) Tablet, Extended Release. I see potassium citrate offered as a vitamin supplement (99mg). This increases the urinary pH and further enhances the clearance of citrate, thus increasing urine citrate concentration. The answer is no, these are not equivalent products. Available for Android and iOS devices. Summary: Potassium is an essential mineral found in many fiber-rich whole foods. Magnesium citrate acts as a laxative by increasing water concentration within the intestines. Select one or more newsletters to continue. It contains 38.28% potassium by mass. So 20 mEq is 20 mmol. Effect of Potassium Citrate on Calcium Phosphate Stones       in a Model of Hypercalciuria. Potassium Citrate is the potassium salt form of citrate with alkalinizing property. RO. Can potassium citrate cause bloating and gas. Potassium citrate in particular produces alkalizing effects in the body, helping to balance urinary pH levels. chloride containing 8 mEq, 10 mEq and 20 mEq of potassium chloride, USP, equivalent to 600 mg, 750 mg and 1500 mg of potassium, respectively, in a film-coated (not enteric-coated), wax matrix tablet. Lexicomp. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Its electron configuration is 1s2 2s2 2p6 3s2 3p6 4s1. Use of potassium citrate alone or in combination with Ca citrate sustains the alkali load that reduces bone loss and enhances intestinal Ca absorption in non-stone formers [83] and stone formers [84]. General considerations. Identical in appearance and size, both medications were prepared as wax matrix formulations by the Mission Pharmacal Company (San Antonio, TX, USA). Accessed 7/31/2015 . Potassium chloride extended-release tablets should be taken with meals and with a glass of water or other liquid. The Potassium Chloride Extended-Release Tablets USP, 20 mEq product is an immediately dispersing extended-release oral dosage form of potassium chloride containing 1,500 mg of microencapsulated potassium chloride, USP equivalent to 20 mEq of potassium in a tablet. DESCRIPTION. The maximum infusion rate of potassium chloride should not exceed 10 mEq/L per hour in a peripheral IV and 40 mEq/L per hour in a central line. The following information includes only the average doses of these medicines. Potassium citrate is a moderately priced drug used to prevent kidney stones.It is more popular than comparable drugs. Urinary alkalinizer for situations in which sodium citrate is contraindicated. For example, Healthline notes that 75 milligrams of potassium chloride salt is equal to 1 milliequivalent of potassium, and 108 milligrams of potassium citrate is equal to 1 milliequivalent of potassium as well. If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Alcoholics, people who underwent bariatric surgery, AIDS patients, and those with eating disorders are at increased risk of developing hypokalemia. The dose medicines in this class will be different for different patients. And it would take four 99 mg capsules to approximate 10 mEq... the .05 difference should be inconsequential. The Potassium Chloride Extended Release Tablets, USP 20 mEq product is an immediately dispersing extended release oral dosage form of potassium chloride containing 1500 mg of microencapsulated potassium chloride, USP equivalent to 20 mEq of potassium in a tablet. I have summarized my findings in the table below. Potassium citrate USP is a white granular powder that is soluble in water at 154 g/100 ml, almost insoluble in alcohol, and insoluble in organic solvents. Hey! Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Potassium citrate is equivalent to the brand-name drug, Urocit-K. What are side effects of potassium citrate? Can Potassium Citrate cause leg crams and muscel spasims? {33} Usual adult prescribing limits Up to 100 mEq of potassium a day. Blood and urinary pH is more popular than comparable drugs serum potassium, urinary and. 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