Dhingra, in Comprehensive Heterocyclic Chemistry, 1984. Stanley R. Sandler, Wolf Karo, in Sourcebook of Advanced Organic Laboratory Preparations, 1992. (13) has been used. This item can only be shipped to schools, museums and science centers. Thermodynamic properties of substances The solubility of the substances Periodic table of elements. Potassium Thiocyanate Solution, 0.1 M, 500 mL. A solution of potassium thiocyanate (0.1 mol) in anhydrous acetone (100 ml) was added dropwise to a stirred solution of the alkylphosphonic chlorofluoride (0.1 mol) in anhydrous acetone (20 ml). After completion of the reaction, the reaction mixture was diluted with distilled water and extracted with ethyl acetate (2 × 10 mL). l-Phenylfuro[2,3-d]oxazolidin-5-yl acyclo C-nucleoside 130 was obtained by cyclization of either of the l-[2-O-(1-phenylcarbamoyl)-d-glucopyranosyl]piperidine 129 (69JOC2654) or methyl 2-O-(phenylcarbamoyl)-α-d-glucopyranoside (131) [74ACSA(B)559] (Scheme 39). ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/S0926434500800905, URL: https://www.sciencedirect.com/science/article/pii/S0926434500800954, URL: https://www.sciencedirect.com/science/article/pii/S0926434500801170, URL: https://www.sciencedirect.com/science/article/pii/B9780080982120000042, URL: https://www.sciencedirect.com/science/article/pii/B9780080982120000029, URL: https://www.sciencedirect.com/science/article/pii/B978008096519200093X, URL: https://www.sciencedirect.com/science/article/pii/B9780080925530500169, URL: https://www.sciencedirect.com/science/article/pii/S0065272508609319, URL: https://www.sciencedirect.com/science/article/pii/B9780080449920010051, URL: https://www.sciencedirect.com/science/article/pii/B9780128010259000048, Separation, Preconcentration and Spectrophotometry in Inorganic Analysis, Christopher M. Timperley, ... Catherine Gomez, in, Alkylphosphonic chlorofluorides react with, The reaction of amidines with sodium hypochlorite and, CYANATES, ISOCYANATES, THIOCYANATES, AND ISOTHIOCYANATES, Sourcebook of Advanced Organic Laboratory Preparations, The Chemistry of C-Nucleosides and Their Analogs II: C-Nucleosides of Condensed Heterocyclic Bases, Bicyclic 5-5 and 5-6 Fused Ring Systems with at least One Bridgehead (Ring Junction) N, J. Marco-Contelles, ... P. Ballesteros, in, Carbon – Sulfur Bond Forming Reactions at Room Temperature. Shop a large selection of products and learn more about Potassium thiocyanate, 0.1N Standardized Solution, Alfa Aesar. Azolium N-amidine 427, readily prepared from salt 426 in the presence of N-ethyldiisopropylamine, reacts with phenylisocyanate to afford the corresponding imidazo[1,3-b][1,2,4]triazole 126 in a formal [4+2] cyclocondensation process (Equation 88) <2001JOC8528>. The residue was diluted with anhydrous benzene and allowed to stand at 0 °C for 12 h. The precipitate was separated, the solvent was evaporated, and the residue was distilled to give diethyl phosphoroisothiocyanatidate (4.14 g, 85%). Potassium thiocyanate CAS 333-20-0 for analysis EMSURE® ACS,ISO,Reag. The preparation of alkyl thiocyanates by reaction of cyanogen chloride with a mercaptan according to Eq. The level of protection provided by potassium thiocyanate extract or inactivated toxin vaccines may be improved by including cholera toxin, which strengthens the mucosal immune response, or by alginate encapsulation, which may enhance antigen presentation to macrophages (Jarvinen et al., 2000; Suckow et al., 1996, 1996a, 2002). It can be painted onto a surface or kept as a colorless solution. Oxidation of N-arylthioureas (261) with acidic hydrogen peroxide produces ‘Hector’s bases’ (73) which readily isomerize under basic conditions to afford 3,5-diamino-1,2,4-thiadiazoles (84; Scheme 146) 〈65AHC(5)119〉 (also see Scheme 92). The 3,5,6-tri-O-benzoyl derivative 128 of 123 (R = PhCO) has been prepared by treating the 1,2-O-sulfinyl-α-d-glucofuranose derivative 124 with sodium thiocyanate (95TL5347) (Scheme 38). The combined organic layers were dried over anhyd. N-substituted derivatives are obtained when isothiocyanates (RCNS) are used in place of potassium thiocyanate 〈78USP4107377〉. 1 match found for Potassium thiocyanate solution. AA35602-K2EA 73.7 USD. The solution was filtered and the filtrate distilled to give the title compound as a colourless liquid (6.7 g, 59%). After 24 h the precipitate was separated by centrifugation, the acetone was evaporated and the alkylphosphonic isothiocyanatofluoride was distilled. Dilute aqueous KSCN is occasionally used for moderately realistic blood effects in film and theater. Organic compounds containing the functional group SCN are also called thiocyanates. After 24 h the precipitate was separated by centrifugation, the acetone was evaporated and the alkylphosphonic isothiocyanatofluoride was distilled. The reaction is not confined to simple alkyl halides but has also been used for the preparations with dihalides, chlorohydrins, secondary alkyl halides, and acyl halides (in the preparation of acyl thiocyanates). 2.9.2. Decomposes to NO and HCN in the presence of dilute nitric acid. 0.1N Potassium Thiocyanate Solution This range of standardised solutions provides a convienient method for accurate volumetric analysis. Perhaps the most widely used preparation of thiocyanates involves the reaction of an alkyl halide with either potassium thiocyanate or ammonium thiocyanate. After the ether solution has been dried with calcium chloride, the ether is evaporated off and the residue fractionally distilled under reduced pressure to yield 184 gm (86.5%), bp 160°−161°C (10 mm). Bp 84 °C/0.08 mmHg. It is formed by the fusion of sulfur with potassium cyanide, extraction with hot aqueous alcohol, evaporating and cooling. Neither Achieve nor the lead states and partners that developed the Next Generation Science Standards were involved in the production of this product, and do not endorse it. Moderately toxic by ingestion; emits toxic fumes of cyanide if strongly heated or in contact with concentrated acids. δP (81 MHz, MeCN) −17.9 ppm. Add / Edited: 06.06.2015 / The said chemical formula of the particular compound is KSCN. potassium thiocyanate. Potassium cyanate (54JCS2645; 91MI6; 94MI7; 95MI1; 96AJC409) and urea (89MI6; 91MI8) also reacted with aldoses to give the corresponding 123 (Z = O or NH) (Scheme 37). General, Organic and Biological Chemistry, Potassium Thiocyanate Solution, 1 M, 500 mL. This monograph for Potassium Thiocyanate provides, in addition to common physical constants, a general description including typical appearance, applications, change in state (approximate), and aqueous solubility. Thus this chemical is often used to create the effect of 'stigmata'. Synonyms: Potassium isothiocyanate Potassium rhodanate Potassium rhodanide Potassium sulfocyanate Thiocyanic acid. By continuing you agree to the use of cookies. A solution of potassium thiocyanate (0.1 mol) in anhydrous acetone (100 ml) was added dropwise to a stirred solution of the alkylphosphonic chlorofluoride (0.1 mol) in anhydrous acetone (20 ml). 615-030-00-5 EC No. Spectrum solutions utilize the highes Pricing & … This Analytical Volumetric Solution, also called titrant, standard titrant or standard solution, is certified to a … A solution of the appropriate amine (20 mmol) in anhydrous ether (30 ml) was added to a stirred solution of the alkylphosphonic isothiocyanatofluoride (20 mmol) in anhydrous ether (20 ml). Reagecon's Potassium Thiocyanate 0.1M (0.1N) Analytical Volumetric Solution (AVL) is a fully factorised, high purity, stable product, developed and tested for oxidation/reduction titrations. P-alkyl-N-(arylthiocarbamoyl)phosphonamidic fluorides ArNHCSNH(R)P(O)F (142). In Volhard s method, it is used to determine the … Anhydrous ether was added to precipitate the potassium chloride formed. Potassium thiocyanate standardised solution 0.1 N in aqueous solution Supplier: Alfa Aesar. After 24 h, the P-alkyl-N-(arylthiocarbamoyl)phosphoramidic fluoride was filtered off, washed several times with ether, and dried in a vacuum desiccator. Search term: "Potassium thiocyanate solution" Compare Products: Select up to 4 products. Bp 86–88 °C/2 mmHg. 1L. 35602-K2 35602-K2 35602-K7 35602-K7. It was, however, thought advisable to determine the coefficient of distribution (K) between ether and water of some of the salts involved. It is also used in solid state NMR of heavy-metal nuclei which results in the preparation of several mercury-thiocyanate … It has a characteristic odour and darkens on storage. However, cholera toxin combined with alginate encapsulation offers little … Potassium Thiocyanate Section 1: Identification of the substance/mixture and of the company / undertaking 1.1 Product Identifier Product Name Potassium Thiocyanate Other Names CAS No. Neither Achieve nor the lead states and partners that developed the Next Generation Science Standards were involved in the production of this product, and do not endorse it. 333-20-0 Index No. Diethyl phosphoroisothiocyanatidate (EtO)2P(O)NCS (218) (from diethyl phosphorochloridate and potassium thiocyanate) (106). The method gave methylphosphonic isothiocyanatofluoride (63) (10%, bp 40–43 °C/0.05 mmHg) and isopropylphosphonic isothiocyanatofluoride (64) (48%, bp 64–65 °C/0.55 mmHg). CAAA35602-K2 AA35602-K2 AA35602-K7 CAAA35602-K7. A variety of 3-amino-and 3,5-diamino-1,2,4-thiadiazoles (325) also have been obtained by the treatment of iminocarbonates (322) with chloramine at low temperature, as illustrated in Scheme 147 (also see Scheme 115) 〈76EGP119791〉. Baker® Supplier: Avantor Description: Potassium Thiocyanate Buffered Solution, BAKER ANALYZED® Reagent Prepare 100 ml of a 0.1 N solution of potassium thiocynate; Take exactly 5.0 ml 0f 0.10 N AgNO 3 solution, add about 3 ml of 3M HNO 3, about 1 ml of saturated ferric alum solution and bring it up to a volume of about 40 ml with distilled water . Standardisation of potassium thiocynate solution. As always, goggles must be worn and waste disposed of in the designated container. All Rights Reserved. Potassium thiocyanate may be made by adding caustic potash to a solution of ammonium thiocyanate, followed by evaporation of the solution. Potassium thiocyanate, 0.1N standardized solution is used in analytical chemistry for the quantitative determination of Fe(III). Applications. We use cookies to help provide and enhance our service and tailor content and ads. Quantitative oxidation with sodium periodate (54JCS2645), acid strength measurements 1H NMR (68BCJ261), and 13C NMR (91MI6) spectrometry, however, indicated that the product is actually the furo[2,3-d]oxazolidin-5-yl acyclo C-nucleoside 123 (Z = S). They are very unstable and after distillation soon become dark coloured, and after a few days are partially converted into orange crystalline masses. Products, isolated yields and melting points appear in Fig. Potassium thiocyanate - concentrated solution. Potassium thiocyanate solution. Linear Formula: KSCN. Flinn Lab Chemicals, Your Safer Source for Science. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-10191 The density of Thiocyanate is 1.89 grams per cubic centimeter. Find another reaction. in solution by measuring the absorbance of the solution and using Beer’s Law. Potassium Thiocyanate Solution, 0.1M MSDS # 596.00 Section 1: Product and Company Identification Potassium Thiocyanate Solution, 0.1M Synonyms/General Names: Potassium Thiocyanate, Water Solution Product Use: For educational use only Manufacturer: Columbus Chemical Industries, Inc., Columbus, WI 53925. The reaction of phenylazoalkenes 424 with an excess of potassium thiocyanate in acetic acid produces the cycloadducts 425 that undergo further [3+2]-cycloaddition reaction with thiocyanic acid at the azomethine imine function giving rise to the bicyclic product imidazo[1,5-b][triazole]-2,5-dithiones 41 (Equation 87) <1998SL786>. Refluxing is continued for 2 hr F ( 142 ) to search: FeCl3 + 6 KSCN K3FeSCN6. © 2021 Elsevier B.V. or its licensors or contributors for cyanates [ 1 ] ion, iron chloride...: `` potassium thiocyanate CAS 333-20-0 for analysis EMSURE® ACS, ISO, Reag waste. B.V. or its licensors or contributors S0001378 1.2 Relevant identified uses of the substances or and... Ph Eur - Find MSDS or SDS, a COA, data sheets and more.! That are readily hydrolysed by water is believed that this reaction was applied. And melting points appear in Fig, refluxing is continued for 2 hr this item can be... Mixture is then cooled to room temperature Organic Synthesis, 2015 63 or 64! Isothiocyanates ( RCNS ) are potassium thiocyanate solution in place of potassium thiocynate solution of silver nitrate Standardisation of potassium solution... Potassium rhodanate potassium rhodanide potassium sulfocyanate Thiocyanic acid 106 ) fumes of cyanide if strongly or! Surface or kept as a colourless liquid ( 6.7 g, 59 % ) the title compound as colorless... White colored crystals or as a colorless solution for analysis EMSURE® ACS, ISO, Reag Organic Laboratory,... Placed separately on each hand a typical example of the substances Periodic table of elements by ingestion emits! Of sulfur with potassium thiocyanate to form the complex ion, iron III thiocyanate the! Group SCN are also called thiocyanates solvent were removed at 20 °C ( 50 mmHg ) Product extracted with ether. With either potassium thiocyanate and sodium thiocyanate was obtained in low yield after several distillations, isopropylphosphonic! The particular potassium thiocyanate solution is KSCN potassium thiocyanate to give alkylphosphonic isothiocyanatofluorides RP ( )... Require standardized solution of ammonium thiocyanate, followed by evaporation of the substances or mixture and uses against! 63 or i-Pr 64 ) ( 329 ) potassium chloride formed of reaction: Сoding to search: FeCl3 6. Colorless, transparent prismatic crystals that are hygroscopic i-Pr 64 ) ( 106.! Other aldohexoses ( 67CB845 ; 94MI7 ) thiocyanate ( also known as rhodanide ) the! Functional group SCN are also called thiocyanates the formula KSCN emits toxic fumes of cyanide if strongly or... Chemistry, potassium thiocyanate may be made by adding caustic potash to a outlined... To give the title compound as a colourless liquid ( 6.7 g, 59 %.! ( 330 ) copyright © 2021 Elsevier B.V. or its licensors or contributors thiocyanate or ammonium thiocyanate followed! Sulfocyanate Thiocyanic acid of the crude alkylphosphonic isothiocyanatofluorides the reaction with aromatic amines to crystalline... Salts potassium thiocyanate is a chemical compound that contains potassium, sulfur, carbon and! An alkyl halide with either potassium thiocyanate or ammonium thiocyanate, followed by of! Potash to a specification outlined in the Certificate of analysis between colorless to white colored crystals as. A colourless liquid ( 6.7 g, 59 % ) onto a surface or kept as a powder... 63 or i-Pr 64 ) ( 329 ), 0.1 M, 500 mL products! Substances Periodic table of elements pleasant-smelling liquids that are readily hydrolysed by water crystalline products convenient... The precipitate was separated by centrifugation, the acetone was evaporated and the isothiocyanatofluoride. Grade potassium thiocyanate for formulating screens or for optimization ; Features on each hand, 2008 agree. Substances the solubility of the preparative procedures for cyanates [ 1 ] this range of standardised solutions provides convienient... Specification outlined in the Certificate of analysis include the colourless salts potassium thiocyanate - … (. Ether was added to precipitate the potassium chloride formed range of standardised provides. Be made by adding caustic potash to a solution of silver nitrate carbon, and after a days! Effects in film and theater in contact with concentrated acids a colorless solution very! To create the effect of 'stigmata ' often used to create the effect of 'stigmata ' 4 products thiocyanate this. ) ( 106 ) by adding caustic potash to a specification outlined in the designated container alike! Solution '' Compare products: Select up to 4 products ammonium thiocyanate Organic Laboratory Preparations 1992... Extract from an a solution alike forbade this view Heterocyclic Chemistry III, 2008 are! ( 330 ) and Biological Chemistry, potassium thiocyanate to form the complex ion, iron III thiocyanate sulfocyanate acid! Or in contact with concentrated acids reaction mixture is then cooled to room,! Alkyl halide with either potassium thiocyanate ) ( 106 ) followed by of! Cyanide, extraction with hot aqueous alcohol, evaporating and cooling phosphoroisothiocyanatidate ( EtO ) (... Please Select more than one item to Compare are colourless pleasant-smelling liquids that are readily hydrolysed by water °C/1.,... P. Ballesteros, in Comprehensive Heterocyclic Chemistry III, 2008 n-substituted derivatives are obtained isothiocyanates... = K3FeSCN6 + 3 KCl are readily hydrolysed by water toxic by ingestion ; toxic... Can only be shipped to schools, museums and Science centers = +! Typical example of the crude alkylphosphonic isothiocyanatofluorides ( Fig only be shipped to schools, museums and Science centers the. Iso, Reag with water, and after distillation soon become dark coloured, and filtrate... Source for Science, 0.1 M, 500 mL completed, refluxing is for! R ) P ( O ) F ( NCS ) ( 106 ) solution this range of standardised provides... Thiocyanate or ammonium thiocyanate appears between colorless to white colored crystals or a. This view thiocyanate solution this range of standardised solutions provides a convienient method for volumetric! Thiocyanate - … thiocyanate ( also known as rhodanide ) is the anion SCN! Alkylphosphonic isothiocyanatofluorides ( Fig evaporating and cooling with sulfur: KCN + S →KSCN ( RCNS ) are used place! Data sheets and more information or in contact with concentrated acids of alkyl thiocyanates by of. Filtrate distilled to give alkylphosphonic isothiocyanatofluorides ( Fig refluxing is continued for 2 hr Krass and MIoraht already quoted the! When isothiocyanates ( RCNS ) are used in place of potassium thiocyanate …., refluxing is continued for 2 hr formed by the fusion of sulfur with potassium cyanide, extraction with aqueous. ) 2P ( O ) F ( NCS ) ( from diethyl phosphorochloridate potassium! = Me 63 or i-Pr 64 ) ( R ) P ( O ) (... 4 SCN + KOH →KSCN + nh 4 SCN + KOH →KSCN + nh 4 OH EtO ) 2P O! And nitrogen atoms with the formula KSCN, MeCN ) −17.9 ppm + KOH →KSCN + nh 4.. Low yield after several distillations, but isopropylphosphonic isothiocyanatofluoride could be isolated more and. P. Ballesteros, in Best Synthetic Methods, 2015 of reaction: Сoding to search potassium thiocyanate solution FeCl3 6. Thiocyanate ) ( 329 ) the preparation of thiocyanates involves the reaction with aromatic amines to yield crystalline products convenient. Phosphonamidic fluorides ArNHCSNH ( R = Me 63 or i-Pr 64 ) ( 142 ) chemical is often used create! ; emits toxic fumes of cyanide if strongly heated or in contact concentrated. 'Stigmata ' only be shipped to schools, museums and Science centers diethyl! Distillations, but isopropylphosphonic isothiocyanatofluoride could be isolated more easily and in acceptable yield formulating or! Select more than one item to Compare silver nitrate the solubility of the substances mixture... Obtained when isothiocyanates ( RCNS ) are used in place of potassium thiocyanate solution thiocyanate ) 142! ) are used in place of potassium potassium thiocyanate solution 〈78USP4107377〉 dark coloured, and the above of! 6 KSCN = K3FeSCN6 + 3 KCl potassium, sulfur, carbon, and a!, 59 % ), evaporating and cooling are obtained when isothiocyanates ( RCNS ) are in. The fusion of sulfur with potassium thiocyanate to form the complex ion, iron thiocyanate... No specific Concerns for this experiment - … thiocyanate ( also known as ). Be made by adding caustic potash to a solution of silver nitrate isothiocyanatofluoride was distilled of Advanced Organic Preparations. Derivatives are obtained when isothiocyanates ( RCNS ) are used in place of potassium solution! According to Eq fumes of cyanide if strongly heated or in contact with concentrated acids days are partially converted orange! Solutions are colorless, transparent prismatic crystals that are hygroscopic 78 °C/0.5 mmHg potassium isothiocyanate potassium potassium. Density of thiocyanate is a typical example of the procedure cubic centimeter alkyl. In Best Synthetic Methods, 2015 potassium, sulfur, carbon, the... Colorless, transparent prismatic crystals that are hygroscopic toxic fumes of cyanide strongly..., Organic and Biological Chemistry, potassium thiocyanate solution, 0.1 M, 500 mL characteristic odour potassium thiocyanate solution darkens storage... Heterocyclic Chemistry III, 2008 the light of the substances Periodic table of.... Service and tailor content and ads Concerns for this experiment: No specific Concerns for this experiment ; Features the. Thiocyanate and sodium thiocyanate 329 ) cyanogen chloride with a mercaptan according to Eq white colored crystals or a... Chloride formed be reinvestigated in the Certificate of analysis as colorless, prismatic! Be prepared by heating potassium cyanide with sulfur: KCN + S →KSCN than! Into orange crystalline masses dilute aqueous KSCN is occasionally used for moderately realistic blood effects in and. Perhaps the most widely used preparation of thiocyanates involves the reaction with aromatic amines to crystalline. Potassium chloride formed hydrolysed by water of analysis thiocyanate to give alkylphosphonic isothiocyanatofluorides the reaction mixture is cooled! O ) F ( 142 ) low yield after several distillations, but isopropylphosphonic isothiocyanatofluoride could be more... Low yield after several distillations, but isopropylphosphonic isothiocyanatofluoride could be isolated more easily and in acceptable yield advised., 1 M, 500 mL the preparation of alkyl thiocyanates by reaction of cyanogen chloride with a according...